A.274 Infusion during 60 min of L-NMMA to healthy volunteers
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چکیده
منابع مشابه
Electroencephalographic approximate entropy changes in healthy volunteers during remifentanil infusion.
BACKGROUND The aim of this study was to investigate the independent effect of remifentanil on the approximate entropy (ApEn) in frontoparietal montages. The authors investigated which montages were relevant to assess the remifentanil effect on the electroencephalogram. Spectral edge frequency and the canonical univariate parameter were used as comparators. METHODS Twenty-eight healthy volunte...
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Accepted for publication 20 January 1995 Abstract Objective-To investigate changes in the electrocardiographic QT interval during rapidly induced, sustained hypocalcaemia in healthy volunteers. Design-Serial rate corrected QT measurements were made during and after a variable rate trisodium citrate infusion designed to "clamp" the whole blood ionised calcium concentration 0-20 mmol/l below base...
متن کاملDynamic assessment of the electrocardiographic QT interval during citrate infusion in healthy volunteers.
OBJECTIVE To investigate changes in the electrocardiographic QT interval during rapidly induced, sustained hypocalcaemia in healthy volunteers. DESIGN Serial rate corrected QT measurements were made during and after a variable rate trisodium citrate infusion designed to "clamp" the whole blood ionised calcium concentration 0.20 mmol/l below baseline for 120 min. SUBJECTS 12 healthy teetotal...
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OBJECTIVES Two randomized Phase I studies in separate populations of healthy adult volunteers investigated the pharmacokinetics, safety and tolerability of daptomycin (Cubicin; Novartis Pharma AG, Basel, Switzerland) administered as a 2 min intravenous (iv) injection, relative to the currently licensed 30 min iv infusion. METHODS Study 1 was an open-label, single-dose, two-period, crossover s...
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CONTEXT During the inflammatory acute phase response, plasma glucose and serum triglycerides are increased in humans. Fibroblast growth factor (FGF) 21 has plasma glucose and lipid-reducing actions, but its role in the acute inflammatory response in human is unknown. OBJECTIVE To investigate circulating levels of FGF21 after lipopolysaccharide (LPS) infusion. DESIGN Two randomized, single-b...
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ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1996
ISSN: 0007-0912
DOI: 10.1016/s0007-0912(18)31129-2